WebAug 12, 2024 · The human thiamine pyrophosphate transporter TPC (SLC25A19) was initially identified as a deoxynucleotide transporter ( 39 ), but its main function is the transport of thiamine pyrophosphate, which is an important co-factor in dehydrogenase reactions ( 99 ). WebFeb 9, 2024 · In mammals, the proteins that transport copper across the inner mitochondrial membrane remain unknown. We previously reported that the mitochondrial carrier family protein Pic2 in budding yeast is a copper importer. The closest Pic2 ortholog in mammalian cells is the mitochondrial phosphate carrier SLC25A3.
The Cell Membrane - Structure - Phospholipids
Phosphate carrier protein, mitochondrial is a protein that in humans is encoded by the SLC25A3 gene. The encoded protein is a transmembrane protein located in the mitochondrial inner membrane and catalyzes the transport of phosphate ions across it for the purpose of oxidative phosphorylation. There are two … See more The SLC25A3 gene is located on the q arm of chromosome 12 in position 23.1 and spans 8,376 base pairs. The gene has 9 exons and produces a 40.1 kDa protein composed of 362 amino acids. The encoded protein … See more The encoded protein (PHC) catalyzes the transport of phosphate from the cytosol into the mitochondrial matrix, either by proton See more The encoded protein interacts with PPIF; this interaction is impaired by CsA. See more • Dolce V, Fiermonte G, Messina A, Palmieri F (1992). "Nucleotide sequence of a human heart cDNA encoding the mitochondrial phosphate carrier". DNA Sequence. 2 (2): … See more Mutations in this gene can cause mitochondrial phosphate carrier deficiency (MPCD), a fatal disorder of oxidative phosphorylation. Symptoms include lactic acidosis, hypertrophic cardiomyopathy, and neonatal hypotonia; afflicted patients die within the first … See more • Solute carrier family See more WebPhosphate carrier protein, mitochondrial Alternative names Phosphate transport protein ( PTP) Solute carrier family 25 member 3 Gene names Name SLC25A3 Synonyms PHC ORF … how to shred frozen chicken
5.3 Active Transport - Biology 2e OpenStax
WebMar 5, 2024 · In active transport, as carrier proteins are used to move materials against their concentration gradient, these proteins are known as pumps. As in other types of cellular … WebFor instance, in the figure below, a carrier protein lets sodium ions move down their gradient, but simultaneously brings a glucose molecule up its gradient and into the cell. The carrier protein uses the energy of the sodium gradient to drive the transport of glucose molecules. WebNational Center for Biotechnology Information notts history